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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
27.58
Human Site:
S191
Identified Species:
46.67
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
S191
C
G
F
S
N
L
E
S
Q
V
L
E
K
R
A
Chimpanzee
Pan troglodytes
XP_518477
346
39236
S191
C
G
F
S
N
L
E
S
Q
V
L
E
K
R
A
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
S191
C
G
F
S
N
L
E
S
Q
V
L
E
K
R
A
Dog
Lupus familis
XP_538923
388
42549
S233
F
G
F
S
N
V
E
S
Q
V
L
E
K
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
S186
C
G
F
S
N
L
E
S
Q
D
L
E
K
R
A
Rat
Rattus norvegicus
NP_001101670
340
38058
S185
C
G
F
S
N
L
E
S
Q
D
L
E
K
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
S180
A
G
F
S
D
Q
S
S
R
V
L
E
K
R
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
N186
C
G
F
S
N
V
D
N
Q
V
L
V
R
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
N176
W
T
I
A
N
R
T
N
E
H
I
V
L
D
S
Honey Bee
Apis mellifera
XP_001120828
342
39209
N187
C
M
L
L
G
K
V
N
E
Q
L
V
L
D
A
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
E110
E
T
R
S
Q
Q
D
E
E
R
A
N
F
L
E
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
S198
A
G
F
V
N
R
T
S
E
N
L
S
L
S
A
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
Q169
G
I
R
N
K
E
N
Q
I
L
S
K
K
F
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
G186
P
G
L
R
N
K
H
G
E
T
L
V
K
S
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
66.6
N.A.
N.A.
60
N.A.
6.6
20
6.6
40
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
N.A.
N.A.
93.3
N.A.
40
33.3
20
46.6
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
0
0
0
0
0
8
0
0
0
72
% A
% Cys:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
15
0
0
15
0
0
0
15
0
% D
% Glu:
8
0
0
0
0
8
43
8
36
0
0
50
0
0
8
% E
% Phe:
8
0
65
0
0
0
0
0
0
0
0
0
8
8
8
% F
% Gly:
8
72
0
0
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
8
15
0
0
0
0
0
8
65
0
8
% K
% Leu:
0
0
15
8
0
36
0
0
0
8
79
0
22
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
72
0
8
22
0
8
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
15
0
8
50
8
0
0
0
8
0
% Q
% Arg:
0
0
15
8
0
15
0
0
8
8
0
0
8
50
0
% R
% Ser:
0
0
0
65
0
0
8
58
0
0
8
8
0
15
8
% S
% Thr:
0
15
0
0
0
0
15
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
8
0
15
8
0
0
43
0
29
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _